Diabetes, Periodontitis and The Oral Microbiome
The association between diabetes mellitus and periodontitis has been studied thoroughly. However, the role of the oral microbiome in linking these two diseases still is not clear. The objective of this literature review is to search the current studies on oral dysbiosis in the two diseases and find out whether the oral microbiome could be a possible biomarker indicating diabetes in periodontal patients. The dynamic relationship between periodontal disease and diabetes mellitus still requires attention. There has been no singular cellular mechanism identified to explain the association between them. Currently, there is inconclusive evidence as to if the oral microbiome can serve as biomarkers for the diagnosis or risk determination of diabetes mellitus. Further clinical research is needed in order to identify biomarkers from the oral microbiome in the destructive relationship between diabetes mellitus and periodontitis.
Author(s): Madison West, DDS ’23, Kaitlin Liautaud, DDS ’23, C. Hunter Pitts, DDS ’23, Michael Ricupito, DDS ’23, Joshua Young Cho, DDS ’22
Mentor(s): Dr. Xiaoyuan Han and Dr. Traci Pitts
Personalized Instructional Program Bench/Clinical Research Award